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saco-indonesia.com, Sebanyak 11 pecatur muda Indonesia di bawah usia 17 tahun memborong medali dalam kejuaraan "World School Chess Championship 2013" dan juara utama the 5th Alexader the Great 2013 di Chalkidiki Yunani.

LONDON, Saco-Indonesia.com - Sebanyak 11 pecatur muda Indonesia di bawah usia 17 tahun memborong medali dalam kejuaraan "World School Chess Championship 2013" dan juara utama the 5th Alexader the Great 2013 di Chalkidiki Yunani.
     
Sekretaris Pertama Fungsi Pensosbud KBRI Athena Jani Sasanti kepada Antara London, Kamis, mengatakan kejuaraan catur dunia yang berlangsung sejak 7 berakhir 14 Mei itu diikuti 567 peserta dari 30 negara termasuk negara yang kuat dalam olah raga catur yaitu Rusia, India,Inggris dan Turki.
     
Pada World School Chess Champions 2013, Indonesia menyabet juara kedua untuk kelompok usia U-9 yaitu Diajeng Theresa Singgih dari Jabar dan juara ketiga kelompok U-15 yaitu Aay Aisyah Anisa dari Jatim, sedang peserta Indonesia muda lainnya berada di ranking 10 besar juara.
     
Sementara pada Kejuaraan the 5th Alexander the Great Open Championship 2013 yang berlangsung di tempat yang sama, Grand Master (GM) Indonesia Irene Kharima Sukandar memenangkan juara utama turnamen bergensi tersebut.
     
Duta Besar RI untuk Yunani Benny Bahanadewa menyampaikan kebangganya atas prestasi yang dicapai pecatur muda Indonesia yang telah mengharumkan nama Indonesia di ajang internasional dan menunjukkan Indonesia memiliki banyak GM yang akan mengantarkan Indonesia sebagai negara pecatur dunia.
     
Keikutsertan peserta Indonesia berasal dari peserta Olympiade Olah Raga Siswa Nasional (02SN) Kementerian Dikbud RI dan PB Percasi, mengikutsertakan 11 pecatur muda katagori U-9, U-11, U-13 dan U-15.
     
Sementara itu, Wakil PB Percasi Yenny Chaidir mengungkapkan kegembiraannya atas kemenangan Indonesia dan akan terus berpartisiapsi pada setiap kejuaraan international dengan harapan Indonesia dapat meningkatkan prestasinya di ajang percaturan dunia.
     
Seri Kejuaraan School Chess Internasional 2013 diselenggarakan FIDE Greece berlangsung sejak 2005 dan Yunani menjadi tempat penyelengaraan pertama kejuraan ini tahun 2009. Pada tahun 2011, kejuaraan tersebut berlangsung di Polandia. Indonesia berhasil merebut lima  kali posisi juara pada periode 2005-2009. 

 

Sumber :ANT/Kompas.com
Editor :Liwon Maulana(galipat)

Satu demi satu misteri penyebab diabetes melitus tipe 2 mulai terungkap.

Oleh IRWAN JULIANTO

Saco-Indonesia.com,- Satu demi satu misteri penyebab diabetes melitus tipe 2 mulai terungkap. Para peneliti Harvard School of Public Health (HSPH) baru saja memublikasikan temuan mereka bahwa ada satu jenis protein atau hormon khusus yang ditemukan dalam sel-sel lemak yang terbukti membantu mengatur bagaimana gula darah dikendalikan dan dimetabolisasi untuk energi di dalam hati. Ini dikatakan akan membuka salah satu jalan bagi pengobatan diabetes tipe 2 yang menjangkiti ratusan juta penduduk dunia.

Diabetes tipe ini tidak bergantung pada insulin dan terjadi pada orang-orang dewasa (adult onset), berbeda dengan diabetes tipe 1 yang bergantung pada insulin dan terjadi sejak bayi. Diabetes tipe 2 dapat didefinisikan sebagai suatu kelainan metabolik yang ditandai dengan tingginya kadar glukosa darah akibat terjadinya kekurangan dan resistansi insulin. Kemampuan sel-sel beta pankreas berkurang bahkan rusak sehingga pasien mulai mengalami diabetes, dengan gejala-gejala seperti banyak makan (polifagia), banyak minum (polidipsia), dan banyak kencing (poliuria).

Jumlah kasus diabetes tipe 2 hampir sepuluh kali lipat kasus diabetes tipe 1 yang terjadi karena kerusakan pankreas sejak bayi. Hingga sekarang diyakini bahwa kegemukan menjadi penyebab utama terjadinya diabetes tipe 2 pada orang-orang yang memang secara genetis sudah membawa gen pembawa penyakit ini.

Dua-tiga dekade lalu sudah diketahui adanya hubungan antara kegemukan dan diabetes tipe 2, tetapi belum jelas apakah kegemukan memicu diabetes jenis ini ataukah hanya mempercepat terjadinya. Riset di Amerika Serikat menunjukkan, orang-orang dengan obesitas tiga kali lebih mudah terjangkit diabetes dibandingkan dengan mereka yang tidak kegemukan. Makin tua seseorang, risiko terkena diabetes tipe 2 juga kian besar. Orang-orang berusia 65 tahun, misalnya, lebih mungkin terserang dibandingkan dengan mereka yang berusia di bawah 20 tahun.

Diabetes tipe 2 juga diketahui erat hubungannya dengan faktor keturunan. Jika dalam keluarga Anda ada yang mengidap diabetes, kemungkinan Anda terjangkit diabetes cukup besar.

Jika ayah atau ibu Anda dan kakek atau nenek serta bibi atau paman Anda menderita penyakit ini, peluang Anda mengalami diabetes tipe 2 mendekati 85 persen. Jika ayah dan nenek mengidap diabetes, risiko Anda cuma 60 persen. Jika hanya ibu yang menderita, maka 22 persen risikonya bagi Anda akan menderita pula.

Diabetes tipe 2 umumnya terjadi pada orang dewasa akibat perubahan gaya hidup, berkurangnya kegiatan jasmani, dan jenis makanan/minuman yang serba fast food dan soft drink. Namun, saat ini diabetes tipe 2 ditemukan juga pada anak- anak dan remaja di Asia.

Penyakit kronis ini diyakini menyebabkan usia harapan hidup bagi penderitanya sepuluh tahun lebih pendek dibandingkan dengan orang-orang non-diabetik akibat komplikasi penyakit jantung koroner, stroke, dan gagal ginjal. Diabetes tipe 2 juga menyebabkan kecacatan, seperti kebutaan akibat komplikasi retinopati dan meningkatnya risiko sebesar 20 kali amputasi tungkai bawah. Pengidap diabetes ini mudah lupa dan mengalami impotensi.

Multipatologi

Selama berpuluh tahun para peneliti dan dokter dihadapkan pada misteri: tidak semua orang yang kegemukan atau resistan terhadap insulin mengidap diabetes tipe 2. Bahkan, cukup banyak orang yang amat gemuk tak terserang penyakit ini. Para ilmuwan lalu berteori bahwa ada suatu faktor yang tak dikenal yang terlibat dalam metabolisme glukosa dalam hati, dan mungkin kehadiran atau absennya elemen ini, dapat menentukan siapa yang terkena diabetes tipe 2.

Dalam jurnal Cell Metabolism edisi 7 Mei 2013, para peneliti HSPH mengungkapkan, dunia ilmiah sudah lama mengetahui bahwa salah satu peristiwa kunci bagi berkembangnya diabetes tipe 2 adalah produksi glukosa yang tak terkontrol dari hati.

”Namun, mekanisme yang mendasarinya tetap masih sukar dipahami,” kata Gökhan S Hotamisligil, Kepala Departemen Genetika dan Penyakit-penyakit Kompleks, dan JS Simmons, profesor genetika dan metabolisme di HSPH. ”Kami sekarang berhasil mengidentifikasi aP2 sebagai suatu hormon baru yang dikeluarkan dari sel-sel lemak yang mengontrol fungsi kritis ini.”

Lewat percobaan dengan mencit di laboratorium memakai teknologi mutakhir ditemukan bahwa jika jumlah aP2 berlebih, timbullah diabetes. Sebaliknya, jika hormon ini diblok atau di- switch-off, produksi glukosa dari hati dapat dikontrol lebih baik sehingga manifestasinya berupa diabetes tipe 2 dan penyakit-penyakit metabolik lainnya pun dapat dicegah.

Kemampuan sebuah organ—dalam hal ini jaringan lemak—begitu langsung dan menentukan dalam mengendalikan tindakan organ lain, yaitu hati, amat menarik, kata Hotamisligil. ”Kami menduga sistem komunikasi antara jaringan lemak dan hati telah berevolusi untuk membantu sel-sel lemak memberi komando kepada hati untuk menyuplai tubuh dengan glukosa pada saat-saat terjadinya kekurangan nutrien. Betapa pun, ketika sel-sel lemak yang membesar kehilangan kendali terhadap sinyal ini karena kondisi obesitas, tingkat aP2 dalam darah naik, glukosa diguyurkan ke dalam aliran darah dan tidak dapat dibersihkan oleh jaringan-jaringan lain. Hasilnya adalah tingginya kadar glukosa darah dan diabetes 2.”

Guru Besar FK UI yang mendalami diabetes, Sidartawan Soegondo, menyatakan, temuan para ilmuwan Harvard ini merupakan sumbangan berarti bagi perkembangan ilmu kedokteran. ”Akhir-akhir ini saya mengajarkan bahwa diabetes tipe 2 adalah penyakit dengan multipatologi,” ujarnya ketika dihubungi pada Selasa (21/5). Kini, selain organ pankreas, diabetes tipe 2 diketahui pula dipicu juga oleh metabolisme sembilan organ lain, antara lain hati dan ginjal.

 

Sumber :Kompas Cetak/http://health.kompas.com/read/2013/05/22/06524140/Harapan.Baru.untuk.Terapi.Diabetes.Tipe.2
Editor :Liwon Maulana

BALTIMORE — In the afternoons, the streets of Locust Point are clean and nearly silent. In front of the rowhouses, potted plants rest next to steps of brick or concrete. There is a shopping center nearby with restaurants, and a grocery store filled with fresh foods.

And the National Guard and the police are largely absent. So, too, residents say, are worries about what happened a few miles away on April 27 when, in a space of hours, parts of this city became riot zones.

“They’re not our reality,” Ashley Fowler, 30, said on Monday at the restaurant where she works. “They’re not what we’re living right now. We live in, not to be racist, white America.”

As Baltimore considers its way forward after the violent unrest brought by the death of Freddie Gray, a 25-year-old black man who died of injuries he suffered while in police custody, residents in its predominantly white neighborhoods acknowledge that they are sometimes struggling to understand what beyond Mr. Gray’s death spurred the turmoil here. For many, the poverty and troubled schools of gritty West Baltimore are distant troubles, glimpsed only when they pass through the area on their way somewhere else.

Photo
 
Officers blocked traffic at Pennsylvania and West North Avenues after reports that a gun was discharged in the area. Credit Drew Angerer for The New York Times

And so neighborhoods of Baltimore are facing altogether different reckonings after Mr. Gray’s death. In mostly black communities like Sandtown-Winchester, where some of the most destructive rioting played out last week, residents are hoping businesses will reopen and that the police will change their strategies. But in mostly white areas like Canton and Locust Point, some residents wonder what role, if any, they should play in reimagining stretches of Baltimore where they do not live.

“Most of the people are kind of at a loss as to what they’re supposed to do,” said Dr. Richard Lamb, a dentist who has practiced in the same Locust Point office for nearly 39 years. “I listen to the news reports. I listen to the clergymen. I listen to the facts of the rampant unemployment and the lack of opportunities in the area. Listen, I pay my taxes. Exactly what can I do?”

And in Canton, where the restaurants have clever names like Nacho Mama’s and Holy Crepe Bakery and Café, Sara Bahr said solutions seemed out of reach for a proudly liberal city.

“I can only imagine how frustrated they must be,” said Ms. Bahr, 36, a nurse who was out with her 3-year-old daughter, Sally. “I just wish I knew how to solve poverty. I don’t know what to do to make it better.”

The day of unrest and the overwhelmingly peaceful demonstrations that followed led to hundreds of arrests, often for violations of the curfew imposed on the city for five consecutive nights while National Guard soldiers patrolled the streets. Although there were isolated instances of trouble in Canton, the neighborhood association said on its website, many parts of southeast Baltimore were physically untouched by the tumult.

Tensions in the city bubbled anew on Monday after reports that the police had wounded a black man in Northwest Baltimore. The authorities denied those reports and sent officers to talk with the crowds that gathered while other officers clutching shields blocked traffic at Pennsylvania and West North Avenues.

Lt. Col. Melvin Russell, a community police officer, said officers had stopped a man suspected of carrying a handgun and that “one of those rounds was spent.”

Colonel Russell said officers had not opened fire, “so we couldn’t have shot him.”

Photo
 
Lambi Vasilakopoulos, right, who runs a casual restaurant in Canton, said he was incensed by last week's looting and predicted tensions would worsen. Credit Drew Angerer for The New York Times

The colonel said the man had not been injured but was taken to a hospital as a precaution. Nearby, many people stood in disbelief, despite the efforts by the authorities to quash reports they described as “unfounded.”

Monday’s episode was a brief moment in a larger drama that has yielded anger and confusion. Although many people said they were familiar with accounts of the police harassing or intimidating residents, many in Canton and Locust Point said they had never experienced it themselves. When they watched the unrest, which many protesters said was fueled by feelings that they lived only on Baltimore’s margins, even those like Ms. Bahr who were pained by what they saw said they could scarcely comprehend the emotions associated with it.

But others, like Lambi Vasilakopoulos, who runs a casual restaurant in Canton, said they were incensed by what unfolded last week.

“What happened wasn’t called for. Protests are one thing; looting is another thing,” he said, adding, “We’re very frustrated because we’re the ones who are going to pay for this.”

There were pockets of optimism, though, that Baltimore would enter a period of reconciliation.

“I’m just hoping for peace,” Natalie Boies, 53, said in front of the Locust Point home where she has lived for 50 years. “Learn to love each other; be patient with each other; find justice; and care.”

A skeptical Mr. Vasilakopoulos predicted tensions would worsen.

“It cannot be fixed,” he said. “It’s going to get worse. Why? Because people don’t obey the laws. They don’t want to obey them.”

But there were few fears that the violence that plagued West Baltimore last week would play out on these relaxed streets. The authorities, Ms. Fowler said, would make sure of that.

“They kept us safe here,” she said. “I didn’t feel uncomfortable when I was in my house three blocks away from here. I knew I was going to be O.K. because I knew they weren’t going to let anyone come and loot our properties or our businesses or burn our cars.”

Even as a high school student, Dave Goldberg was urging female classmates to speak up. As a young dot-com executive, he had one girlfriend after another, but fell hard for a driven friend named Sheryl Sandberg, pining after her for years. After they wed, Mr. Goldberg pushed her to negotiate hard for high compensation and arranged his schedule so that he could be home with their children when she was traveling for work.

Mr. Goldberg, who died unexpectedly on Friday, was a genial, 47-year-old Silicon Valley entrepreneur who built his latest company, SurveyMonkey, from a modest enterprise to one recently valued by investors at $2 billion. But he was also perhaps the signature male feminist of his era: the first major chief executive in memory to spur his wife to become as successful in business as he was, and an essential figure in “Lean In,” Ms. Sandberg’s blockbuster guide to female achievement.

Over the weekend, even strangers were shocked at his death, both because of his relatively young age and because they knew of him as the living, breathing, car-pooling center of a new philosophy of two-career marriage.

“They were very much the role models for what this next generation wants to grapple with,” said Debora L. Spar, the president of Barnard College. In a 2011 commencement speech there, Ms. Sandberg told the graduates that whom they married would be their most important career decision.

In the play “The Heidi Chronicles,” revived on Broadway this spring, a male character who is the founder of a media company says that “I don’t want to come home to an A-plus,” explaining that his ambitions require him to marry an unthreatening helpmeet. Mr. Goldberg grew up to hold the opposite view, starting with his upbringing in progressive Minneapolis circles where “there was woman power in every aspect of our lives,” Jeffrey Dachis, a childhood friend, said in an interview.

The Goldberg parents read “The Feminine Mystique” together — in fact, Mr. Goldberg’s father introduced it to his wife, according to Ms. Sandberg’s book. In 1976, Paula Goldberg helped found a nonprofit to aid children with disabilities. Her husband, Mel, a law professor who taught at night, made the family breakfast at home.

Later, when Dave Goldberg was in high school and his prom date, Jill Chessen, stayed silent in a politics class, he chastised her afterward. He said, “You need to speak up,” Ms. Chessen recalled in an interview. “They need to hear your voice.”

Years later, when Karin Gilford, an early employee at Launch Media, Mr. Goldberg’s digital music company, became a mother, he knew exactly what to do. He kept giving her challenging assignments, she recalled, but also let her work from home one day a week. After Yahoo acquired Launch, Mr. Goldberg became known for distributing roses to all the women in the office on Valentine’s Day.

Ms. Sandberg, who often describes herself as bossy-in-a-good-way, enchanted him when they became friendly in the mid-1990s. He “was smitten with her,” Ms. Chessen remembered. Ms. Sandberg was dating someone else, but Mr. Goldberg still hung around, even helping her and her then-boyfriend move, recalled Bob Roback, a friend and co-founder of Launch. When they finally married in 2004, friends remember thinking how similar the two were, and that the qualities that might have made Ms. Sandberg intimidating to some men drew Mr. Goldberg to her even more.

Over the next decade, Mr. Goldberg and Ms. Sandberg pioneered new ways of capturing information online, had a son and then a daughter, became immensely wealthy, and hashed out their who-does-what-in-this-marriage issues. Mr. Goldberg’s commute from the Bay Area to Los Angeles became a strain, so he relocated, later joking that he “lost the coin flip” of where they would live. He paid the bills, she planned the birthday parties, and both often left their offices at 5:30 so they could eat dinner with their children before resuming work afterward.

Friends in Silicon Valley say they were careful to conduct their careers separately, politely refusing when outsiders would ask one about the other’s work: Ms. Sandberg’s role building Facebook into an information and advertising powerhouse, and Mr. Goldberg at SurveyMonkey, which made polling faster and cheaper. But privately, their work was intertwined. He often began statements to his team with the phrase “Well, Sheryl said” sharing her business advice. He counseled her, too, starting with her salary negotiations with Mark Zuckerberg.

“I wanted Mark to really feel he stretched to get Sheryl, because she was worth it,” Mr. Goldberg explained in a 2013 “60 Minutes” interview, his Minnesota accent and his smile intact as he offered a rare peek of the intersection of marriage and money at the top of corporate life.

 

 

While his wife grew increasingly outspoken about women’s advancement, Mr. Goldberg quietly advised the men in the office on family and partnership matters, an associate said. Six out of 16 members of SurveyMonkey’s management team are female, an almost unheard-of ratio among Silicon Valley “unicorns,” or companies valued at over $1 billion.

When Mellody Hobson, a friend and finance executive, wrote a chapter of “Lean In” about women of color for the college edition of the book, Mr. Goldberg gave her feedback on the draft, a clue to his deep involvement. He joked with Ms. Hobson that she was too long-winded, like Ms. Sandberg, but aside from that, he said he loved the chapter, she said in an interview.

By then, Mr. Goldberg was a figure of fascination who inspired a “where can I get one of those?” reaction among many of the women who had read the best seller “Lean In.” Some lamented that Ms. Sandberg’s advice hinged too much on marrying a Dave Goldberg, who was humble enough to plan around his wife, attentive enough to worry about which shoes his young daughter would wear, and rich enough to help pay for the help that made the family’s balancing act manageable.

Now that he is gone, and Ms. Sandberg goes from being half of a celebrated partnership to perhaps the business world’s most prominent single mother, the pages of “Lean In” carry a new sting of loss.

“We are never at 50-50 at any given moment — perfect equality is hard to define or sustain — but we allow the pendulum to swing back and forth between us,” she wrote in 2013, adding that they were looking forward to raising teenagers together.

“Fortunately, I have Dave to figure it out with me,” she wrote.

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